Used in pharmaceutical research as a key intermediate in the synthesis of selective kinase inhibitors, particularly in the development of targeted cancer therapies. Its rigid polycyclic structure enhances binding affinity to specific enzyme active sites, improving inhibitor potency. Also explored in the design of PET radiotracers due to its ability to cross the blood-brain barrier, enabling imaging of neurological targets. Shows promise in medicinal chemistry for optimizing drug candidates with improved metabolic stability and selectivity.