Used in pharmaceutical research as a chiral intermediate for synthesizing bioactive molecules, particularly in the development of central nervous system agents. Its rigid polycyclic structure and stereoselective properties make it valuable in optimizing drug candidates for improved binding affinity and metabolic stability. Commonly employed in asymmetric synthesis and catalysis due to its ability to induce high enantioselectivity in carbon-carbon bond-forming reactions. Also explored in the design of novel enzyme inhibitors owing to its structural similarity to natural indene derivatives with biological activity.