4-[(S)-4-Boc-2-methyl-1-piperazinyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)pyrido[2,3-d]pyrimidin-2(1H)-one
98%
Reagent
Code: #232859
CAS Number
2252403-85-1
blur_circular Chemical Specifications
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Molecular Information
Weight
606.6628 g/mol
Formula
C₃₂H₃₆F₂N₆O₄
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Registry Numbers
MDL Number
MFCD32068509
thermostat
Physical Properties
Boiling Point
703.6±70.0 °C(Predicted)
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Storage & Handling
Density
1.33±0.1 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of Janus kinase (JAK) inhibitors, particularly in the development of targeted therapies for inflammatory and autoimmune diseases such as rheumatoid arthritis and psoriasis. Its structural features enable selective modulation of JAK enzyme activity, contributing to reduced cytokine signaling and inflammation. The compound’s design supports improved pharmacokinetic properties, including metabolic stability and oral bioavailability, making it valuable in optimizing drug candidates for clinical use.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Off-white to Gray Solid |
| Purity (%) | 97.5-100% |
| LC-MS | Conforms to Structure |
| NMR | Conforms to Structure |
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