(5R,6S)-Allyl 6-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-7-oxo-3-((R)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
98%
Reagent
Code: #230234
CAS Number
120705-67-1
blur_circular Chemical Specifications
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Molecular Information
Weight
439.64 g/mol
Formula
C₂₁H₃₃NO₅SSi
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Registry Numbers
MDL Number
MFCD09039289
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Physical Properties
Boiling Point
536.3 ºC at 760mmHg
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Storage & Handling
Density
1.16 g/cm3
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of carbapenem antibiotics, which are broad-spectrum beta-lactam antibiotics effective against a wide range of Gram-positive and Gram-negative bacteria, including multidrug-resistant strains. Its structure enables the construction of the core beta-lactam ring system essential for antibacterial activity. The silyl protecting group and allyl ester functionalities allow for selective reactions during stepwise assembly of the final active pharmaceutical ingredient. Commonly employed in controlled environments for the preparation of advanced intermediates in antibiotic development.
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