(6R,7R)-4-Methoxybenzyl 7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride
95%
Reagent
Code: #230155
CAS Number
113479-65-5
blur_circular Chemical Specifications
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Molecular Information
Weight
405.3 g/mol
Formula
C₁₆H₁₈Cl₂N₂O₄S
thermostat
Physical Properties
Melting Point
155-157°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of cephalosporin antibiotics, particularly third-generation cephalosporins. Its structure allows for side-chain modifications that enhance antimicrobial activity and resistance to beta-lactamase enzymes. Commonly employed in pharmaceutical manufacturing to produce broad-spectrum antibiotics effective against Gram-negative bacteria. The hydrochloride salt form improves stability and solubility during synthesis. Widely utilized in semi-synthetic antibiotic development due to its reactive chloromethyl group, enabling further chemical derivatization.
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