2-Oxo-1,2-dihydroquinoline-6-carboxylic acid
95%
Reagent
Code: #222107
CAS Number
70639-78-0
blur_circular Chemical Specifications
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Molecular Information
Weight
189.17 g/mol
Formula
C₁₀H₇NO₃
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Registry Numbers
MDL Number
MFCD11007961
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Physical Properties
Melting Point
>300 °C
Boiling Point
487.7 °C at 760 mmHg
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the production of third-generation quinolones like sparfloxacin and gatifloxacin. Its structure provides the essential quinoline core that contributes to the antibacterial activity by inhibiting bacterial DNA gyrase and topoisomerase IV. It is also employed in the development of new antimicrobial agents and in medicinal chemistry research for designing analogs with improved potency and reduced side effects. Additionally, it serves as a building block in the preparation of various heterocyclic compounds for pharmaceutical applications.
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