Used as a key intermediate in the synthesis of biologically active quinazoline derivatives, particularly in pharmaceuticals targeting kinase inhibitors for cancer therapy. It serves as a building block in medicinal chemistry for developing compounds with antitumor, antibacterial, and anti-inflammatory properties. Its nitro group allows for further functionalization, enabling the creation of diverse derivatives for structure-activity relationship studies. Also employed in the development of fluorescent probes and sensors due to the inherent photophysical properties of the quinazoline core.