3-Methyl-2-thioxo-2,3,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(1H)-one
97%
science Other reagents with same CAS 38201-61-5
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description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of potent kinase inhibitors, particularly targeting cyclin-dependent kinases (CDKs) involved in cancer cell proliferation. Its structure supports high binding affinity to ATP-binding sites in kinases, making it valuable in developing anti-tumor agents. Also explored in the design of selective inhibitors for inflammatory and neurodegenerative diseases due to its ability to cross the blood-brain barrier. Commonly employed in structure-activity relationship (SAR) studies to optimize drug candidates for improved metabolic stability and potency.
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