1-Methyl-1H-indazole-5-sulfonylchloride
97%
Reagent
Code: #202921
CAS Number
1097730-93-2
blur_circular Chemical Specifications
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Molecular Information
Weight
230.67 g/mol
Formula
C₈H₇ClN₂O₂S
thermostat
Physical Properties
Boiling Point
376.9±15.0 °C(Predicted)
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Storage & Handling
Density
1.55±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used primarily as an intermediate in organic synthesis, especially in the development of pharmaceuticals and agrochemicals. Its sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamide and sulfonate ester derivatives. Commonly employed in medicinal chemistry for modifying bioactive molecules, it aids in enhancing metabolic stability and binding affinity. Also utilized in the preparation of kinase inhibitors and other biologically active compounds. Its indazole core contributes to improved pharmacokinetic properties in drug design.
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