6-Hydroxy-1,5-naphthyridine-3-carboxylic acid
98%
Reagent
Code: #196692
CAS Number
1508822-90-9
blur_circular Chemical Specifications
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Molecular Information
Weight
190.158 g/mol
Formula
C₉H₆N₂O₃
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Registry Numbers
MDL Number
MFCD30471560
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of fluoronaphthyridinone antibiotics, particularly in the production of broad-spectrum antimicrobial agents. Its structure enables the formation of chelating motifs that enhance metal binding in active sites of bacterial enzymes, improving drug efficacy. Also employed in the development of quinolone analogs with improved pharmacokinetic profiles, including better solubility and reduced resistance development. Additionally, it serves as a building block in medicinal chemistry for designing inhibitors targeting DNA gyrase and topoisomerase IV in pathogenic bacteria.
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