6-Hydroxy-1,5-naphthyridine-3-carboxylic acid
98%
science Other reagents with same CAS 1508822-90-9
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description Product Description
Used as a key intermediate in the synthesis of fluoronaphthyridinone antibiotics, particularly in the production of broad-spectrum antimicrobial agents. Its structure enables the formation of chelating motifs that enhance metal binding in active sites of bacterial enzymes, improving drug efficacy. Also employed in the development of quinolone analogs with improved pharmacokinetic profiles, including better solubility and reduced resistance development. Additionally, it serves as a building block in medicinal chemistry for designing inhibitors targeting DNA gyrase and topoisomerase IV in pathogenic bacteria.
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