4-Chloro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-indazol-3-amine

98%

Reagent Code: #192438
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CAS Number 2189684-53-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 375.58 g/mol
Formula C₁₅H₁₈BClF₃N₃O₂
badge Registry Numbers
MDL Number MFCD34471206
thermostat Physical Properties
Boiling Point 462.5±45.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.39±0.1 g/cm3(Predicted)
Storage 2-8°C, light-proof, inert gas

description Product Description

Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active indazole derivatives. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in pharmaceutical research, particularly in the development of kinase inhibitors and other targeted therapies. The trifluoroethyl and chloro substituents enhance reactivity and selectivity in coupling processes, allowing for the construction of complex molecular architectures found in drug candidates. Commonly employed in medicinal chemistry for lead optimization and library synthesis.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿1,330.00
inventory 250mg
10-20 days ฿2,660.00
inventory 1g
10-20 days ฿4,370.00

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