5-Fluoro-7-methoxyquinazolin-4(3H)-one
97%
Reagent
Code: #188099
CAS Number
944742-29-4
science Other reagents with same CAS 944742-29-4
blur_circular Chemical Specifications
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Molecular Information
Weight
194.16 g/mol
Formula
C₉H₇FN₂O₂
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Registry Numbers
MDL Number
MFCD13191851
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Physical Properties
Boiling Point
333.7±52.0°C at 760 mmHg
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Storage & Handling
Storage
Room temperature, dry seal
description Product Description
Used as a key intermediate in the synthesis of epidermal growth factor receptor (EGFR) inhibitors, particularly in targeted cancer therapies. Its structure allows for selective modification at the 4-position and 7-position, making it valuable in developing tyrosine kinase inhibitors. Commonly employed in pharmaceutical research for lung, breast, and glioblastoma cancer drug candidates. Also utilized in structure-activity relationship (SAR) studies to optimize potency and selectivity of quinazoline-based drugs.
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