5-Fluoro-7-methoxyquinazolin-4(3H)-one

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Reagent Code: #188099
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CAS Number 944742-29-4

science Other reagents with same CAS 944742-29-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 194.16 g/mol
Formula C₉H₇FN₂O₂
badge Registry Numbers
MDL Number MFCD13191851
thermostat Physical Properties
Boiling Point 333.7±52.0°C at 760 mmHg
inventory_2 Storage & Handling
Storage Room temperature, dry seal

description Product Description

Used as a key intermediate in the synthesis of epidermal growth factor receptor (EGFR) inhibitors, particularly in targeted cancer therapies. Its structure allows for selective modification at the 4-position and 7-position, making it valuable in developing tyrosine kinase inhibitors. Commonly employed in pharmaceutical research for lung, breast, and glioblastoma cancer drug candidates. Also utilized in structure-activity relationship (SAR) studies to optimize potency and selectivity of quinazoline-based drugs.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿1,150.00
inventory 250mg
10-20 days ฿2,320.00
inventory 1g
10-20 days ฿6,230.00

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5-Fluoro-7-methoxyquinazolin-4(3H)-one
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Used as a key intermediate in the synthesis of epidermal growth factor receptor (EGFR) inhibitors, particularly in targeted cancer therapies. Its structure allows for selective modification at the 4-position and 7-position, making it valuable in developing tyrosine kinase inhibitors. Commonly employed in pharmaceutical research for lung, breast, and glioblastoma cancer drug candidates. Also utilized in structure-activity relationship (SAR) studies to optimize potency and selectivity of quinazoline-based drugs.
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