Used as a key intermediate in the synthesis of quinazoline-based pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective functionalization, making it valuable in creating compounds with high biological activity. Commonly employed in research settings to design drugs targeting epidermal growth factor receptor (EGFR) and other tyrosine kinases. Also utilized in the preparation of fluorescent probes due to its electron-withdrawing substituents, which enhance photophysical properties.