Used primarily in pharmaceutical research as a key intermediate in the synthesis of potent neurokinin-1 (NK1) receptor antagonists. It plays a critical role in developing compounds that modulate the central nervous system, particularly for treating nausea and vomiting associated with chemotherapy. Its structure enables high affinity binding to NK1 receptors, making it valuable in creating antiemetic drugs with improved efficacy and fewer side effects. Additionally, derivatives based on this scaffold are explored for potential anxiolytic and antidepressant activities.