7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine
97%
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Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and central nervous system (CNS) active compounds. Its structure supports functionalization at multiple sites, making it valuable in medicinal chemistry for constructing complex heterocyclic systems. Commonly employed in cross-coupling reactions such as Suzuki and Buchwald-Hartwig aminations to build biaryl or arylamine linkages found in bioactive molecules. Also utilized in the preparation of selective serotonin reuptake inhibitors (SSRIs) and related antidepressant candidates. Its stability and reactivity profile make it suitable for late-stage derivatization in drug discovery programs.
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