Phoyunnanin E exhibits significant antifungal activity, particularly against plant pathogens such as Magnaporthe oryzae, which causes rice blast disease. This makes it a promising candidate for development as a natural fungicide in agricultural applications. Its ability to inhibit spore germination and mycelial growth helps protect crops without relying on synthetic chemicals. Additionally, Phoyunnanin E shows moderate cytotoxic effects against certain human cancer cell lines, suggesting potential in pharmaceutical research for anticancer agents. Due to its natural origin and bioactivity, it is also studied for use in eco-friendly pest management and as a lead compound in drug discovery.