1-(((2S,3R)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole
98%
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description Product Description
This compound serves as a key chiral intermediate in the synthesis of triazole-based azole fungicides, both for agricultural and pharmaceutical applications. It is particularly used in the production of systemic fungicides that inhibit ergosterol biosynthesis, essential for fungal cell membrane integrity, thereby disrupting fungal growth and reproduction.
The derived agricultural fungicides effectively control a broad spectrum of fungal diseases in crops, including powdery mildew, rusts, and leaf spots in cereals, fruits, and vegetables. These products exhibit systemic properties, being absorbed by plant tissues to provide both preventive and curative activity. They are typically applied as foliar sprays or seed treatments, offering long-lasting protection, improving crop yield and quality, and demonstrating stability across diverse environmental conditions.
In pharmaceutical contexts, this intermediate is employed in synthesizing antifungal agents for treating human fungal infections, such as chronic skin conditions or systemic mycoses. Its specific stereochemical configuration enhances binding efficiency to fungal targets while minimizing side effects on human cells, though many such applications are still in research or development stages.
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