NH2-PEG-OH is widely used in bioconjugation and drug delivery systems due to its biocompatibility and ability to enhance solubility. It serves as a linker molecule in the modification of proteins, peptides, and other biomolecules, improving their stability and reducing immunogenicity. In drug delivery, it is utilized to create PEGylated drugs, which exhibit prolonged circulation time in the body and targeted delivery to specific tissues. Additionally, it plays a role in surface functionalization of nanoparticles, enabling better dispersion and controlled release of therapeutic agents. Its applications also extend to tissue engineering, where it is used to modify scaffolds for improved cell adhesion and growth.