MAL-PEG-MAL is widely used in bioconjugation and drug delivery systems due to its bifunctional reactive groups. It serves as a linker to connect biomolecules such as proteins, peptides, or antibodies with other functional entities, enhancing their stability and targeting efficiency. In drug delivery, it facilitates the creation of polymer-drug conjugates, improving solubility and prolonging circulation time in the body. Additionally, it is employed in surface modification of nanoparticles, enabling controlled release and targeted delivery of therapeutic agents. Its applications also extend to the development of hydrogels and biomaterials for tissue engineering, where it aids in creating crosslinked networks with tailored properties.