tert-Butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxapentadecan-15-oate
97%
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This chemical is primarily utilized in the field of bioconjugation and protein modification. It serves as a linker molecule, enabling the attachment of various functional groups or molecules to proteins or peptides. Its structure, featuring a reactive pyrrole dione moiety, allows for efficient and selective conjugation under mild conditions. This makes it valuable in the development of antibody-drug conjugates (ADCs), where it helps in linking cytotoxic drugs to antibodies for targeted cancer therapy. Additionally, it is employed in the synthesis of polymer-drug conjugates, enhancing the solubility and stability of therapeutic agents. The compound’s polyethylene glycol (PEG) chain further improves biocompatibility and reduces immunogenicity, making it suitable for biomedical applications.
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