Used in bioconjugation to link biomolecules such as peptides, proteins, or antibodies through reductive amination, leveraging its aldehyde groups for stable bond formation. Commonly applied in drug delivery systems to create PEGylated therapeutics, enhancing solubility and reducing immunogenicity. Serves as a crosslinker in hydrogel formation for tissue engineering and wound healing applications due to its multi-arm structure enabling 3D network formation. Aldehyde termini allow for pH-sensitive and selective reactions under mild conditions, making it suitable for encapsulating sensitive biologicals. Also utilized in surface modification of nanoparticles and medical devices to improve biocompatibility and reduce protein adsorption.