Propargyl-peg6-acid
95%
blur_circular Chemical Specifications
description Product Description
Used in bioconjugation and pharmaceutical research, this compound serves as a linker in the synthesis of antibody-drug conjugates (ADCs) and targeted therapeutics. Its propargyl group enables click chemistry reactions, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), allowing efficient and selective attachment to azide-functionalized molecules. The PEG6 spacer enhances solubility, reduces aggregation, and improves pharmacokinetic properties by increasing hydrophilicity and reducing nonspecific binding. The terminal carboxylic acid group can be activated for amide bond formation with amines, enabling conjugation to proteins, peptides, or small molecules. Commonly applied in the development of diagnostic probes, targeted drugs, and biomolecule labeling strategies.
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