Used in bioconjugation and pharmaceutical research to link biomolecules with improved solubility and stability. The Boc-protected amine allows for controlled deprotection and selective coupling, while the long PEG8 spacer reduces steric hindrance and enhances flexibility between functional groups. Commonly employed in the synthesis of peptide-drug conjugates, PEGylated compounds, and targeted therapeutics. The terminal carboxylic acid enables easy activation and attachment to amines or hydroxyls on proteins, peptides, or surfaces. Ideal for creating linkers in antibody-drug conjugates (ADCs) and diagnostic probes where water solubility and biocompatibility are critical.