Acrylate-PEG-NH2 is widely used in bioconjugation and polymer chemistry due to its dual functional groups. The acrylate group readily undergoes radical polymerization, enabling crosslinking in hydrogels and polymer networks. This makes it valuable in tissue engineering scaffolds and drug delivery systems where controlled matrix formation is required.

The amine (NH2) terminus allows for easy coupling with carboxylic acids, activated esters (like NHS esters), or aldehydes, facilitating the attachment of peptides, proteins, drugs, or fluorescent labels. Its PEG spacer provides water solubility, reduces non-specific binding, and enhances biocompatibility.

It is commonly used in surface modification of biomaterials and medical devices, where the acrylate anchors to a polymer backbone and the amine serves as a reactive handle for further functionalization. It’s also employed in creating PEGylated surfaces in biosensors and diagnostic platforms to improve stability and reduce fouling.