Ald-Ph-amido-PEG3-C-COOH

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Reagent Code: #133300
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CAS Number 1007215-91-9

science Other reagents with same CAS 1007215-91-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 339.34 g/mol
Formula C₁₆H₂₁NO₇
badge Registry Numbers
MDL Number MFCD20228912
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used in bioconjugation and pharmaceutical research, this compound serves as a bifunctional linker that combines an aldehyde group with a carboxylic acid terminus through a hydrophilic PEG3 spacer. The aldehyde group readily reacts with primary amines to form Schiff bases, which can be reduced to stable secondary amines, enabling efficient coupling to proteins, peptides, or amine-containing molecules. The terminal carboxylic acid allows for activation and subsequent amide bond formation with nucleophiles such as amines, making it ideal for constructing complex bioconjugates like antibody-drug conjugates (ADCs) or targeted therapeutics. The PEG3 segment enhances water solubility and improves the pharmacokinetic properties of the resulting conjugates by reducing aggregation and increasing biocompatibility. Its design supports modular assembly in drug delivery systems, diagnostics, and surface functionalization of biomaterials.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿37,950.00

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Ald-Ph-amido-PEG3-C-COOH
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Used in bioconjugation and pharmaceutical research, this compound serves as a bifunctional linker that combines an aldehyde group with a carboxylic acid terminus through a hydrophilic PEG3 spacer. The aldehyde group readily reacts with primary amines to form Schiff bases, which can be reduced to stable secondary amines, enabling efficient coupling to proteins, peptides, or amine-containing molecules. The terminal carboxylic acid allows for activation and subsequent amide bond formation with nucleophiles such as amines, making it ideal for constructing complex bioconjugates like antibody-drug conjugates (ADCs) or targeted therapeutics. The PEG3 segment enhances water solubility and improves the pharmacokinetic properties of the resulting conjugates by reducing aggregation and increasing biocompatibility. Its design supports modular assembly in drug delivery systems, diagnostics, and surface functionalization of biomaterials.
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