THP-PEG4-Pyrrolidine(N-Me)-CH2OH
95%
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description Product Description
This compound is primarily utilized in the field of bioconjugation and drug delivery due to its unique structure. The THP (tetrahydropyran) group acts as a protective moiety, ensuring stability during chemical reactions, while the PEG4 (polyethylene glycol) spacer enhances solubility and reduces immunogenicity. The pyrrolidine ring, with its N-methyl substitution, contributes to improved pharmacokinetic properties by increasing metabolic stability. The hydroxymethyl group (-CH2OH) serves as a reactive site for further functionalization, enabling the attachment of targeting ligands or therapeutic agents. This makes it a versatile building block in the synthesis of prodrugs, antibody-drug conjugates, and other targeted delivery systems, particularly in oncology and immunotherapy. Its design allows for controlled release and targeted action, minimizing off-target effects and improving therapeutic efficacy.
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