Trt-PEG4-C2-acid (hydrate) is widely used in the field of bioconjugation and drug delivery. Its primary application lies in its ability to act as a linker molecule, facilitating the attachment of various functional groups or therapeutic agents to larger biomolecules. The PEG (polyethylene glycol) spacer in the compound enhances solubility and reduces immunogenicity, making it suitable for creating biocompatible conjugates. It is particularly useful in the development of antibody-drug conjugates (ADCs), where it helps in connecting cytotoxic drugs to antibodies, ensuring targeted delivery to cancer cells. Additionally, it is employed in peptide synthesis and modification, where its trityl (Trt) protecting group provides stability during chemical reactions. The compound’s versatility also extends to materials science, where it is used to modify surfaces or nanoparticles for enhanced performance in biomedical applications.