T-Butoxycarbonyl-peg2-sulfonic acid is primarily used in organic synthesis and bioconjugation processes. Its application is significant in the modification of peptides and proteins, where it acts as a protecting group for amino acids during solid-phase peptide synthesis. This compound is also utilized in the development of drug delivery systems, particularly in the creation of PEGylated drugs, which enhance the solubility, stability, and bioavailability of therapeutic agents. Additionally, it plays a role in the preparation of functionalized polymers and surfaces, contributing to advancements in materials science and nanotechnology. Its sulfonic acid group further enables its use in catalysis and as a surfactant in various chemical reactions.