m-PEG8-Tos is widely used in bioconjugation and chemical synthesis due to its reactive tosyl group and polyethylene glycol (PEG) chain. It serves as a linker molecule for attaching PEG chains to proteins, peptides, or other biomolecules, enhancing their solubility, stability, and biocompatibility. This compound is particularly valuable in drug delivery systems, where it helps improve the pharmacokinetics and bioavailability of therapeutic agents. Additionally, it is employed in the development of PEGylated drugs, which exhibit prolonged circulation time in the body. Its application also extends to surface modification of nanoparticles and materials, making them more suitable for biomedical applications.