m-PEG6-Ms is widely used in bioconjugation and drug delivery systems due to its ability to improve the solubility, stability, and bioavailability of therapeutic compounds. It serves as a linker in the synthesis of antibody-drug conjugates (ADCs), enabling the attachment of cytotoxic drugs to antibodies for targeted cancer therapy. The compound is also employed in PEGylation processes, where it modifies proteins, peptides, or small molecules to enhance their pharmacokinetic properties and reduce immunogenicity. Additionally, m-PEG6-Ms is utilized in the development of prodrugs, facilitating controlled release and improving therapeutic efficacy. Its mesylate group allows for efficient conjugation with nucleophiles, making it a versatile reagent in organic and medicinal chemistry.