Benzyl-PEG4-THP is widely used in organic synthesis and pharmaceutical research as a versatile protecting group and linker. Its tetrahydropyran (THP) group is particularly useful for protecting alcohols during complex chemical reactions, ensuring selective reactivity in multi-step syntheses. The PEG4 spacer enhances solubility in aqueous and organic solvents, making it suitable for conjugation with various molecules, such as drugs, peptides, or biomolecules. This compound is often employed in the development of prodrugs, targeted drug delivery systems, and bioconjugation strategies, where controlled release or specific targeting is required. Its stability under mild conditions and ease of deprotection make it a valuable tool in medicinal chemistry and biopharmaceutical applications.