N-Methylfulleropyrrolidine is primarily used in organic photovoltaics due to its excellent electron-accepting properties. It enhances the efficiency of solar cells by facilitating charge separation and electron transport when blended with conjugated polymers. This compound is also explored in perovskite solar cells as an interfacial layer to improve device stability and reduce charge recombination. Its unique fullerene-based structure contributes to good thermal stability and tunable electronic characteristics, making it suitable for use in flexible electronics and thin-film devices. Additionally, it has potential applications in molecular electronics and as a component in sensors due to its responsive electronic behavior under external stimuli.

Fulleropyrrolidine derivatives like N-Methylfulleropyrrolidine are also investigated in biomedical research for their antioxidant properties, ability to penetrate cell membranes, and potential in drug delivery systems or treatments for oxidative stress-related diseases.