Phrymarolin V is primarily used in the fragrance and flavor industry due to its unique aromatic properties. It serves as a key ingredient in the formulation of high-end perfumes, where it contributes a fresh, green, and slightly floral note that enhances the overall olfactory profile. Its stability under various pH conditions and moderate temperatures makes it suitable for use in both fine fragrances and functional products like scented cosmetics and personal care items.

In addition to its olfactory applications, Phrymarolin V exhibits antimicrobial properties, which have led to its inclusion in certain preservative systems for cosmetic formulations. It helps extend shelf life by inhibiting the growth of bacteria and fungi without causing skin irritation at recommended concentrations.

Its low volatility and good substantivity on skin allow for long-lasting scent performance, making it valuable in developing fragrance accords with improved tenacity. Ongoing research is also exploring its potential in agricultural applications as a natural pest deterrent due to its structural similarity to certain plant defense compounds.