Methedrone hydrochloride is primarily used in research settings to study its effects on the central nervous system, particularly its stimulant and psychoactive properties. It has been investigated for its potential to influence neurotransmitter release, such as dopamine and serotonin, which helps in understanding the mechanisms of addiction and stimulant-related behaviors. In forensic science, it is analyzed to identify and quantify its presence in biological samples, aiding in legal and regulatory cases involving substance abuse. Additionally, it serves as a reference standard in analytical chemistry to develop and validate methods for detecting similar compounds in various matrices.