Dimethylsilicone oil is widely used as a lubricant in various mechanical systems due to its excellent thermal stability and low viscosity. It is commonly applied in high-temperature environments, such as in automotive engines and industrial machinery, to reduce friction and wear.

In the cosmetic and personal care industry, it is utilized as a key ingredient in skincare products, hair conditioners, and makeup. Its smooth texture helps improve the spreadability of products, while providing a silky feel and enhancing moisture retention.

It also serves as a release agent in manufacturing processes, particularly in the production of rubber, plastics, and metal parts, where it prevents materials from sticking to molds.

In the medical field, it is used in certain medical devices and formulations, such as in syringes and topical treatments, due to its biocompatibility and inert nature.

Additionally, it is employed as a dielectric fluid in electrical applications, offering insulation and protection for sensitive components.