Rebaudioside D is widely used as a natural sweetener in the food and beverage industry due to its high sweetness intensity and low-calorie content. It is particularly favored in products targeting health-conscious consumers, such as sugar-free or reduced-sugar beverages, desserts, and snacks. Its stability under high temperatures makes it suitable for baked goods and processed foods. Additionally, it is often blended with other sweeteners to enhance flavor profiles and reduce aftertaste. In the pharmaceutical industry, it is utilized to improve the palatability of medications, especially in liquid formulations and chewable tablets. Its non-cariogenic properties also make it a popular ingredient in oral care products like toothpaste and mouthwash.