Ethyl acetoacetate is widely used as a key intermediate in the synthesis of pharmaceuticals, dyes, and agrochemicals. It plays an important role in the preparation of various heterocyclic compounds due to its active methylene group and keto-ester functionality. It is commonly employed in the acetoacetic ester synthesis to produce ketones, particularly in the manufacture of antimalarial drugs like chloroquine and antipyretics. It also serves in the production of amino acids, vitamins (such as vitamin B1 and vitamin B6), and cosmetic UV absorbers. In organic synthesis, it acts as a building block for creating pyrazolones and other nitrogen-containing rings used in pigments and pharmaceuticals. Additionally, it finds use in the formulation of flavors and fragrances due to its fruity odor and reactivity.