Used as a reagent in organic synthesis, particularly in the preparation of pentafluorophenyl esters, which are valuable intermediates in peptide and protein chemistry. It is also employed in the modification of polymers and materials to introduce fluorinated groups, enhancing their chemical resistance and stability. Additionally, it finds application in the development of advanced materials and coatings with unique properties, such as hydrophobicity and thermal stability. Its role in facilitating efficient and selective chemical transformations makes it a key component in research and industrial processes.