Ishikawa’s Reagent is primarily used in organic synthesis for the selective fluorination of organic compounds. It is particularly effective in introducing fluorine atoms into aromatic systems, which is valuable in the development of pharmaceuticals and agrochemicals. The reagent is also employed in the synthesis of fluorinated intermediates that are critical in the production of active pharmaceutical ingredients (APIs). Its ability to facilitate mild and efficient fluorination reactions makes it a preferred choice in medicinal chemistry for creating compounds with enhanced biological activity and metabolic stability. Additionally, Ishikawa’s Reagent is utilized in material science for modifying the properties of polymers and other materials by incorporating fluorine atoms, improving their resistance to solvents, heat, and chemical degradation.