Used as a reagent in organic synthesis, particularly in the introduction of the triflyl (trifluoromethanesulfonyl) group to nitrogen-containing compounds. It serves as a triflating agent for amines and amides, enabling the formation of N-triflyl derivatives which are useful intermediates in pharmaceutical and agrochemical synthesis. Its benzyl group can act as a protecting group, allowing selective reactions at other sites in the molecule. Commonly employed in the preparation of sulfonamides with enhanced metabolic stability and bioavailability, making it valuable in medicinal chemistry. Also utilized in the synthesis of catalysts and functional materials where electron-withdrawing sulfonamide groups are required.