Used as a solvent in organic synthesis, particularly for reactions requiring high polarity and low nucleophilicity. It is effective in facilitating the formation of complex molecules, including pharmaceuticals and agrochemicals. Its unique properties make it suitable for use in NMR spectroscopy as a solvent for analyzing compounds with low solubility in common solvents. Additionally, it is employed in the production of specialty polymers and coatings, where its fluorine content enhances thermal stability and chemical resistance.