diethyl (3-(trifluoromethyl)benzyl)phosphonate

≥95%

Reagent Code: #168228
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CAS Number 146780-08-7

science Other reagents with same CAS 146780-08-7

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Weight 296.24 g/mol
Formula C₁₂H₁₆F₃O₃P
inventory_2 Storage & Handling
Storage Room temperature, seal, dry

description Product Description

Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated analogs of bioactive molecules. Its structure enables the introduction of a trifluoromethyl-substituted benzyl group, which can enhance metabolic stability and lipophilicity in drug candidates. Commonly employed in Horner-Wadsworth-Emmons reactions to form fluorinated olefins, which are important motifs in medicinal chemistry. Also utilized in agrochemical research for designing novel active ingredients with improved environmental stability and biological activity.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿1,620.00
inventory 5g
10-20 days ฿38,880.00
inventory 1g
10-20 days ฿11,160.00

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diethyl (3-(trifluoromethyl)benzyl)phosphonate
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Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated analogs of bioactive molecules. Its structure enables the introduction of a trifluoromethyl-substituted benzyl group, which can enhance metabolic stability and lipophilicity in drug candidates. Commonly employed in Horner-Wadsworth-Emmons reactions to form fluorinated olefins, which are important motifs in medicinal chemistry. Also utilized in agrochemical research for designing novel active ingredients with improved environmental stability and biological activity.
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