Used primarily as a specialty ester in organic synthesis, particularly in the preparation of trifluoromethyl-containing compounds. Its reactivity stems from the activated oxalate group paired with the electron-withdrawing trifluoroethyl moiety, making it useful in acylation reactions and as a building block for pharmaceuticals and agrochemicals where fluorinated groups enhance metabolic stability and bioavailability. It serves as a reagent in the formation of ketones, aldehydes, and heterocycles through controlled decomposition or coupling reactions. Due to the fluorine content, it also finds use in the development of materials with unique surface properties, such as water and oil repellency. Handling requires caution due to potential hydrolysis releasing toxic gases.