Used as a key building block in pharmaceutical synthesis, particularly in the development of biologically active compounds. Its strained cyclobutane ring and fluorine substituent enhance metabolic stability and binding affinity in drug candidates. Commonly employed in the preparation of protease inhibitors and CNS-targeted agents due to its favorable conformational properties and ability to mimic peptide motifs. The cis configuration allows for specific stereochemical interactions, making it valuable in structure-activity relationship studies. Also utilized in agrochemicals for designing novel active ingredients with improved potency and selectivity.