Used in organic synthesis as a fluorinated building block, particularly in the preparation of pharmaceuticals and agrochemicals. Its electron-deficient double bond makes it suitable for Michael addition reactions and cycloadditions, enabling the construction of complex fluorinated molecules. The tert-butyl ester group offers stability during reactions and can be easily removed under mild acidic conditions to reveal the corresponding carboxylic acid when needed. Commonly employed in medicinal chemistry for introducing trifluoromethyl-containing motifs, which can enhance metabolic stability, lipophilicity, and bioavailability of drug candidates.