Perfluoroalkyl ethyl iodides are primarily used as intermediates in the synthesis of fluorinated compounds. Their unique structure allows them to introduce perfluoroalkyl groups into larger molecules, which is valuable in creating materials with enhanced thermal, chemical, and oxidative stability. These compounds are widely applied in the production of specialty surfactants, water and oil repellents, and surface modifiers for textiles, paper, and leather. Due to their low surface energy, they improve stain resistance and durability in coatings and finishes. They also serve in the development of fluorinated pharmaceuticals and agrochemicals, where the presence of fluorine can increase bioavailability and metabolic stability. Additionally, they are used in electronic materials and polymers requiring high performance under extreme conditions. Their reactivity makes them useful in radical reactions and polymerization processes, especially in controlled environments where precise functionalization is needed. However, due to environmental concerns around long-chain perfluoroalkyl substances, their use is often limited to short-chain derivatives or contained industrial processes.