(4-(Methoxymethoxy)phenyl)(trifluoromethyl)sulfane
95%
Reagent
Code: #130151
CAS Number
1808089-05-5
blur_circular Chemical Specifications
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Molecular Information
Weight
238.23 g/mol
Formula
C₉H₉F₃O₂S
thermostat
Physical Properties
Boiling Point
210.4±40.0 °C(Predicted)
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Storage & Handling
Density
1.31±0.1 g/cm3(Predicted)
Storage
Room temperature, light-proof, inert gas
description Product Description
Used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its structure, featuring a trifluoromethylthio (-SCF3) group and a methoxymethoxy (MOM)-protected phenyl ring, allows for selective functionalization in multi-step reactions, making it valuable in constructing complex molecules. The trifluoromethylthio group enhances lipophilicity and metabolic stability, which is beneficial in drug design for improving bioavailability and membrane permeability. The MOM group serves as a protecting group for the phenolic hydroxyl, enabling orthogonal deprotection strategies. Commonly employed in the synthesis of bioactive compounds where fluorinated moieties are needed to modulate electronic and steric properties, including anti-inflammatory agents, antimicrobials, and immunomodulators.
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