(4-Fluorophenyl)(mesityl)iodonium trifluoromethanesulfonate
97%
Reagent
Code: #131972
CAS Number
1146127-04-9
blur_circular Chemical Specifications
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Molecular Information
Weight
490.25 g/mol
Formula
C₁₆H₁₅F₄IO₃S
thermostat
Physical Properties
Melting Point
177-178 °C
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Storage & Handling
Storage
Room temperature, light-proof, inert gas
description Product Description
Used as a highly efficient arylating agent in organic synthesis, particularly for transferring the 4-fluorophenyl group under mild conditions. It is valuable in the preparation of fluorinated aromatic compounds, which are important in pharmaceutical and agrochemical research due to their enhanced metabolic stability and binding affinity. Commonly employed in transition-metal-free arylation reactions, it enables C–C, C–O, and C–N bond formation, making it useful in late-stage functionalization of complex molecules. Its stability and reactivity profile make it suitable for use in radiochemistry, especially in fluorine-18 labeling for positron emission tomography (PET) imaging.
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