tert-Butyl(1-ethynyl-3,3-difluorocyclobutyl)carbamate
98%
Reagent
Code: #155787
CAS Number
2316459-53-5
blur_circular Chemical Specifications
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Molecular Information
Weight
231.24 g/mol
Formula
C₁₁H₁₅F₂NO₂
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Registry Numbers
MDL Number
MFCD32670526
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceutical compounds, particularly in the development of bioactive molecules with enhanced metabolic stability and binding affinity. Its strained cyclobutyl core and difluoro substitution pattern contribute to improved pharmacokinetic properties in drug candidates. The tert-butylcarbamate (Boc) group allows for easy protection and deprotection during peptide-like coupling reactions, making it valuable in medicinal chemistry for building complex, fluorinated scaffolds. Commonly employed in research targeting CNS drugs and enzyme inhibitors where fluorine substitution plays a critical role in activity.
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