3-(difluoromethyl)bicyclo[1.1.1]pentane-1-carboxylic acid
95%
Reagent
Code: #167762
CAS Number
2090481-18-6
blur_circular Chemical Specifications
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Molecular Information
Weight
162.13 g/mol
Formula
C₇H₈F₂O₂
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Registry Numbers
MDL Number
MFCD29767889
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key building block in medicinal chemistry, particularly in the development of bioisosteres for drug design. Its unique strained bicyclic structure combined with the difluoromethyl group enhances metabolic stability and modulates lipophilicity, making it valuable in optimizing pharmacokinetic properties of pharmaceutical candidates. Commonly employed in the synthesis of CNS-targeted drugs and anti-inflammatory agents due to its ability to improve blood-brain barrier penetration and reduce off-target effects. Also utilized in agrochemicals to increase compound stability and efficacy under environmental conditions.
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